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. 2019 Aug 28;14(8):e0221828. doi: 10.1371/journal.pone.0221828

Fig 6. Analysis of inulin-induced changes in microbial metabolism in the brain.

Fig 6

Scyllo-inositol was dramatically increased in the hippocampus of E4FAD mice fed the prebiotic inulin compared to the E4FAD mice fed the control diet. (A) Shows the voxel that was used for MRS. Representative spectra are shown for (B) the E3FAD-Control, E4FAD-Control, and E4FAD-Inulin groups. The arrow indicates scyllo-inositol, which was dramatically increased in mice fed the prebiotic inulin. Scyllo-inositol (C) was significantly increased in E4FAD inulin mice compared to control fed E3FAD and E4FAD mice. Myo-inositol (D) was significantly decreased in E4FAD mice fed inulin. Data are the mean ± SEM, n.s. = not significant; ****p < 0.0001.