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. 2019 Jul 24;44(4):1219–1232. doi: 10.3892/ijmm.2019.4287

Figure 11.

Figure 11

miR-29a suppresses the invasion and migration of U2OS and MG-63 osteosarcoma cells through the SOCS1/NF-κB signalling pathway. (A) Migration of cells transfected with miR-29a mimics and/or siSOCS1, examined by wound healing assay (magnification, ×40). (B) Invasion of cells transfected with miR-29a mimics and/or siSOCS1, as measured by the Transwell assay (magnification, ×100). (C) Quantified cell migration rate and (D) number of invaded cells. Data are expressed as the mean ± standard deviation. Comparison among three or more groups was conducted using one-way analysis of variance followed by Tukey's post hoc test. *P<0.05 and **P<0.01. miR-29a, microRNA-29a; SOCS1, suppressor of cytokine signalling 1; siSOCS1, SOCS1 siRNA; NC, negative control.