Skip to main content
. 2019 Aug 13;8:e47328. doi: 10.7554/eLife.47328

Figure 6. ST6GAL1 Expression in Human Multiple Myeloma Cells Correlates Negatively with Bone Marrow Neutrophil Abundance.

(A) Quantification of ST6GAL1 expression in bone marrow histological specimens from treatment-naive multiple myeloma patients (n = 15). (B) Negative correlation between ST6GAL1 expression and frequency of bands and segmented PMNs (p<0.01). Stratification of patients into low and high ST6GAL1 expression was predictive of abundance of segmented neutrophils (**p<0.01, student’s T-test). (C) Representative data from one patient with high and one patient with low myeloma ST6GAL1 expression, showing H and E with neutrophils indicated (left, arrows or arrowheads), and ST6GAL1 stain with myeloma cells indicated (right, arrowheads).

Figure 6.

Figure 6—figure supplement 1. Survival and Plasma Cell Abundance are not altered by ST6GAL1 Expression.

Figure 6—figure supplement 1.

(A) Correlation between ST6GAL1 score and patient survival in months. (B) Correlation between disease burden, enumerated as frequency of plasma cells in the bone marrow, and frequency of neutrophils.