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. 2019 Aug 5;8:e45905. doi: 10.7554/eLife.45905

Figure 5. The unc-2(zf35gf) mutation leads to increased spontaneous EPSCs and decreased spontaneous IPSCs.

Figure 5.

(a) Representative traces of total spontaneous postsynaptic currents (sPSCs) from ventral body wall muscles in wild-type and unc-2(zf35gf) mutants. (b and c) Mean spontaneous PSC frequency and amplitude of wild-type and unc-2(zf35gf) mutants. (d) Representative traces of spontaneous cholinergic EPSCs in unc-49 and unc-49; unc-2(zf35gf) mutants. (e and f) Mean spontaneous EPSC frequency and amplitude unc-49 and unc-49; unc-2(zf35gf) mutants. (g) Representative traces of spontaneous GABAergic IPSCs in wild-type and unc-2(zf35gf) mutants. (h and i) Mean IPSC frequency and amplitude of wild-type animals and unc-2(zf35gf) mutants. Error bars depict SEM. *p<0.05, **p<0.01, two-tailed Student’s t test.

Figure 5—source data 1. Source data for Figure 5.
DOI: 10.7554/eLife.45905.013