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. 2019 Aug 5;8:e45905. doi: 10.7554/eLife.45905
Strain Feature Genotype Figures
CB55 canonical unc-2 loss-of-function unc-2(e55) Figure 2Figure 4
QW37 gain-of-function unc-2 unc-2(zf35gf) All Figures
QW355 unc-2(zf35gf) intragenic suppressor unc-2(zf35gf zf109) Figure 2
QW359 unc-2(zf35gf) intragenic suppressor unc-2(zf35gf zf113) Figure 2
QW360 unc-2(zf35gf) intragenic suppressor unc-2(zf35gf zf114) Figure 2
QW441 unc-2(zf35gf) intragenic suppressor unc-2(zf35gf zf115) Figure 2
QW720 unc-2(zf35gf) intragenic suppressor unc-2(zf35gf zf124) Figure 2
QW726 unc-2(zf35gf) intragenic suppressor unc-2(zf35gf zf130) Figure 2
QW849 unc-2(zf35gf) intragenic suppressor unc-2(zf35gf zf134) Figure 2
QW383 Pan-neuronal expression of UNC-2(GF) lin-15(n765ts); zfEx51[Ptag-168::UNC-2(GF); lin-15(+)] Figure 2, Figure 4
QW388 Pan-neuronal expression of UNC-2(GF) in unc-2(lf) background unc-2(e55); lin-15(n765ts); zfEx51[Ptag-168::UNC-2(GF); lin-15(+)] Figure 2, Figure 4
QW392 Pan-neuronal expression of UNC-2(WT) in unc-2(lf) background unc-2(e55); lin-15(n765ts); zfEx51[Ptag-168::UNC-2(WT); lin-15(+)] Figure 2, Figure 4
QW1632 Cell-specific expression of expression of UNC-2(GF) in GABAergic motor neurons lin-15(n765ts); zfEx801[Punc-47::UNC-2(GF); lin-15(+)] Figure 7—figure supplement 2
QW741 Cell-specific expression of expression of UNC-2(GF) in cholinergic motor neurons lin-15(n765ts); zfEx801[Pacr-2::UNC-2(GF); lin-15(+)] Figure 7—figure supplement 2
QW863 Pan-neuronal expression of UNC-2(FHM S218L) in unc-2(lf) background unc-2(e55); lin-15(n765ts); zfEx51[Ptag-168::UNC-2(FHM1 S218L); lin-15(+)] Figure 4
QW864 Pan-neuronal expression of UNC-2(FHM R192Q) in unc-2(lf) background unc-2(lj1); lin-15(n765ts); zfEx51[Ptag-168::UNC-2(FHM1 R192Q); lin-15(+)] Figure 4
QW1317 Pan-neuronal expression of UNC-2(WT)::GFP in unc-2(lf) background unc-2(e55); lin-15(n765ts); zfEx51[Ptag-168::UNC-2(WT)::GFP; lin-15(+)] Figure 4
QW1362 Pan-neuronal expression of UNC-2(GF)::GFP in unc-2(lf) background unc-2(e55); lin-15(n765ts); zfEx51[Ptag-168::UNC-2(GF)GFP; lin-15(+)] Figure 4
IZ930 Synaptic marker strain for GABAergic synapses ufIs58[Punc-47::RAB-3::mCherry]; oxIs19[Punc-49::UNC-49::GFP] Figure 6, Figure 7,
Figure 6—figure supplements 2 and 3,
Figure 7—figure supplements 1 and 3
IZ106 Synaptic marker strain for nicotinic receptor unc-29(x29); ufIs7[Punc-29::UNC-29::GFP] Figure 6
QW937 Synaptic marker strain for GABAergic synapses in unc-2(zf35gf) background unc-2(zf35gf); ufIs58[Punc-47::RAB-3::mCherry]; oxIs19[Punc-49::UNC-49::GFP] Figure 6, Figure 7, Figure 6—figure supplements 2 and 3,
Figure 7—figure supplements 1 and 3
QW1703 Synaptic marker strain for GABAergic synapses in unc-2(zf35gf);acr-12(lf) background unc-2(zf35gf); acr-12(ok367); ufIs58[Punc-47::RAB-3::mCherry]; oxIs19[Punc-49::UNC-49::GFP] Figure 7Figure 7—figure supplement 1
QW1726 Synaptic marker strain for GABAergic synapses in unc-2(zf35gf);unc-29(lf) background unc-2(zf35gf); unc-29(x29); ufIs58[Punc-47::RAB-3::mCherry]; oxIs19[Punc-49::UNC-49::GFP] Figure 7Figure 7—figure supplement 1
QW1367 Synaptic marker strain for GABAergic synapses with cell-specific expression of UNC-2(GF) in GABAergic neurons ufIs58[Punc-47::RAB-3::mCherry]; oxIs19[Punc-49::UNC-49::GFP]; zfEx609[Punc-47::unc-2(zf35gf);+rol-6(+)] Figure 7, Figure 7—figure supplement 1
QW1375 Synaptic marker strain for GABAergic synapses with cell-specific expression of UNC-2(GF) in cholinergic motor neurons ufIs58[Punc-47::RAB-3::mCherry]; oxIs19[Punc-49::UNC-49::GFP]; zfEx613[Pacr-2::unc-2(zf35gf); rol-6(+)] Figure 7Figure 7—figure supplement 1
QW1849 Synaptic marker strain for GABAA receptor in tax-6(lf) background tax-6(p675); oxIs19[Punc-49::UNC-49::GFP] Figure 7
QW1841 Synaptic marker strain for GABAA receptor in unc-2(zf35gf);tax-6(lf) background unc-2(zf35gf); tax-6(p675); oxIs19[Punc-49::UNC-49::GFP] Figure 7
IZ539 Synaptic marker strain for GABAergic synapses with body wall muscle expression of AChR(GF) akIs26[Pmyo-3::LEV-1(GF);Pmyo-3::UNC-29(GF); lin-15(+)(L-AChR(GF)]; ufIs58[Punc-47::RAB-3::mCherry]; oxIs19[Punc-49::UNC-49::GFP] Figure 7
IZ818 Synaptic marker strain for GABAergic synapses with body wall muscle expression of AChR(WT) ufIs47[Pmyo-3::UNC-38; Pmyo-3::UNC-29;Pmyo-3::LEV-1; lin-15(+) (L-AChR(WT)]; ufIs58[Punc-47::RAB-3::mCherry]; oxIs19[Punc-49::UNC-49::GFP] Figure 7