Strain | Feature | Genotype | Figures |
---|---|---|---|
CB55 | canonical unc-2 loss-of-function | unc-2(e55) | Figure 2, Figure 4 |
QW37 | gain-of-function unc-2 | unc-2(zf35gf) | All Figures |
QW355 | unc-2(zf35gf) intragenic suppressor | unc-2(zf35gf zf109) | Figure 2 |
QW359 | unc-2(zf35gf) intragenic suppressor | unc-2(zf35gf zf113) | Figure 2 |
QW360 | unc-2(zf35gf) intragenic suppressor | unc-2(zf35gf zf114) | Figure 2 |
QW441 | unc-2(zf35gf) intragenic suppressor | unc-2(zf35gf zf115) | Figure 2 |
QW720 | unc-2(zf35gf) intragenic suppressor | unc-2(zf35gf zf124) | Figure 2 |
QW726 | unc-2(zf35gf) intragenic suppressor | unc-2(zf35gf zf130) | Figure 2 |
QW849 | unc-2(zf35gf) intragenic suppressor | unc-2(zf35gf zf134) | Figure 2 |
QW383 | Pan-neuronal expression of UNC-2(GF) | lin-15(n765ts); zfEx51[Ptag-168::UNC-2(GF); lin-15(+)] | Figure 2, Figure 4 |
QW388 | Pan-neuronal expression of UNC-2(GF) in unc-2(lf) background | unc-2(e55); lin-15(n765ts); zfEx51[Ptag-168::UNC-2(GF); lin-15(+)] | Figure 2, Figure 4 |
QW392 | Pan-neuronal expression of UNC-2(WT) in unc-2(lf) background | unc-2(e55); lin-15(n765ts); zfEx51[Ptag-168::UNC-2(WT); lin-15(+)] | Figure 2, Figure 4 |
QW1632 | Cell-specific expression of expression of UNC-2(GF) in GABAergic motor neurons | lin-15(n765ts); zfEx801[Punc-47::UNC-2(GF); lin-15(+)] | Figure 7—figure supplement 2 |
QW741 | Cell-specific expression of expression of UNC-2(GF) in cholinergic motor neurons | lin-15(n765ts); zfEx801[Pacr-2::UNC-2(GF); lin-15(+)] | Figure 7—figure supplement 2 |
QW863 | Pan-neuronal expression of UNC-2(FHM S218L) in unc-2(lf) background | unc-2(e55); lin-15(n765ts); zfEx51[Ptag-168::UNC-2(FHM1 S218L); lin-15(+)] | Figure 4 |
QW864 | Pan-neuronal expression of UNC-2(FHM R192Q) in unc-2(lf) background | unc-2(lj1); lin-15(n765ts); zfEx51[Ptag-168::UNC-2(FHM1 R192Q); lin-15(+)] | Figure 4 |
QW1317 | Pan-neuronal expression of UNC-2(WT)::GFP in unc-2(lf) background | unc-2(e55); lin-15(n765ts); zfEx51[Ptag-168::UNC-2(WT)::GFP; lin-15(+)] | Figure 4 |
QW1362 | Pan-neuronal expression of UNC-2(GF)::GFP in unc-2(lf) background | unc-2(e55); lin-15(n765ts); zfEx51[Ptag-168::UNC-2(GF)GFP; lin-15(+)] | Figure 4 |
IZ930 | Synaptic marker strain for GABAergic synapses | ufIs58[Punc-47::RAB-3::mCherry]; oxIs19[Punc-49::UNC-49::GFP] |
Figure 6, Figure 7, Figure 6—figure supplements 2 and 3, Figure 7—figure supplements 1 and 3 |
IZ106 | Synaptic marker strain for nicotinic receptor | unc-29(x29); ufIs7[Punc-29::UNC-29::GFP] | Figure 6 |
QW937 | Synaptic marker strain for GABAergic synapses in unc-2(zf35gf) background | unc-2(zf35gf); ufIs58[Punc-47::RAB-3::mCherry]; oxIs19[Punc-49::UNC-49::GFP] |
Figure 6, Figure 7, Figure 6—figure supplements 2 and 3, Figure 7—figure supplements 1 and 3 |
QW1703 | Synaptic marker strain for GABAergic synapses in unc-2(zf35gf);acr-12(lf) background | unc-2(zf35gf); acr-12(ok367); ufIs58[Punc-47::RAB-3::mCherry]; oxIs19[Punc-49::UNC-49::GFP] | Figure 7, Figure 7—figure supplement 1 |
QW1726 | Synaptic marker strain for GABAergic synapses in unc-2(zf35gf);unc-29(lf) background | unc-2(zf35gf); unc-29(x29); ufIs58[Punc-47::RAB-3::mCherry]; oxIs19[Punc-49::UNC-49::GFP] | Figure 7, Figure 7—figure supplement 1 |
QW1367 | Synaptic marker strain for GABAergic synapses with cell-specific expression of UNC-2(GF) in GABAergic neurons | ufIs58[Punc-47::RAB-3::mCherry]; oxIs19[Punc-49::UNC-49::GFP]; zfEx609[Punc-47::unc-2(zf35gf);+rol-6(+)] | Figure 7, Figure 7—figure supplement 1 |
QW1375 | Synaptic marker strain for GABAergic synapses with cell-specific expression of UNC-2(GF) in cholinergic motor neurons | ufIs58[Punc-47::RAB-3::mCherry]; oxIs19[Punc-49::UNC-49::GFP]; zfEx613[Pacr-2::unc-2(zf35gf); rol-6(+)] | Figure 7, Figure 7—figure supplement 1 |
QW1849 | Synaptic marker strain for GABAA receptor in tax-6(lf) background | tax-6(p675); oxIs19[Punc-49::UNC-49::GFP] | Figure 7 |
QW1841 | Synaptic marker strain for GABAA receptor in unc-2(zf35gf);tax-6(lf) background | unc-2(zf35gf); tax-6(p675); oxIs19[Punc-49::UNC-49::GFP] | Figure 7 |
IZ539 | Synaptic marker strain for GABAergic synapses with body wall muscle expression of AChR(GF) | akIs26[Pmyo-3::LEV-1(GF);Pmyo-3::UNC-29(GF); lin-15(+)(L-AChR(GF)]; ufIs58[Punc-47::RAB-3::mCherry]; oxIs19[Punc-49::UNC-49::GFP] | Figure 7 |
IZ818 | Synaptic marker strain for GABAergic synapses with body wall muscle expression of AChR(WT) | ufIs47[Pmyo-3::UNC-38; Pmyo-3::UNC-29;Pmyo-3::LEV-1; lin-15(+) (L-AChR(WT)]; ufIs58[Punc-47::RAB-3::mCherry]; oxIs19[Punc-49::UNC-49::GFP] | Figure 7 |