Table 4.

Toxicities associated with mCBAD therapy.

Toxicity	All grades n (%)
Anemia	136 (97.1)
Neutropenia	133 (95)
Thrombocytopenia	131 (93.6)
Infection	52 (37.1)
Febrile neutropenia	36 (25.7)
Neuropathy	34 (24.3)
Gastrointestinal*	20 (13.6)
Thromboembolism	4 (2.8)
Cardiac CHF/Arrhythmia	4 (2.8)
Bleeding**	4 (2.1)
Treatment-related mortality^	11 (7.8)
Sepsis/Septic Shock	6
Multi-organ failure	2
Central nervous system bleeding	2
Respiratory failure (patient with PCL)	1

Reported anemia, neutropenia, and thrombocytopenia were grades 3–4 events according to the common terminology criteria for adverse events (CTCAE) version 5.0.

^*Diarrhea (n=10), Stomatitis (n=4), Nausea/Vomiting (n=3), Transaminitis (n=3).

^**Hematuria (n=2); Central nervous system bleeding (n=2).

^{^}Patient with relapsed/refractory MM (n=10) and plasma cell leukemia (n=1)