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Isobologram analysis of the drug combination treatment
| Substance | Drug concentration | |||
| I | II | III | IV | |
| Interaction: +++, synergism; ++ moderate synergism; -, slight antagonism
Tel (μM): I = 75; II = 50; III = 25; IV = 12.5 Vem (μM): I = 0.9; II = 0.6; III = 0.3; IV = 0.15 | ||||
| Tel | 61.08± | 56.89± | 40.32± | 29.35± |
| Vem | 59.48± | 54.54± | 41.99± | 36.89± |
| Mixture | 69.64± | 69.01± | 66.55± | 61.08± |
| CI | 1.104 | 0.767 | 0.456 | 0.325 |
| Interaction | - | ++ | +++ | +++ |
