S2.
Non-significant association in meta-analysis
| PMID | Gene
(variant) |
Cancer type | Year | Comparison | Ethnicity | OR
(95% CI) |
Publication bias/
heterogeneity |
I2(%) | No.
of studies |
Cases/
control |
Maf |
| 25154002 | ACE1
(rs4646994) |
GC | 2015 | DD+DI vs II | Diverse | 1.06
(0.92–1.21) |
0.791/0.317 | 15.1 | 6 | 4262
(1311/2951) |
0.3746 |
| 27623072 | CCND1
(rs603965) |
GC | 2016 | A vs G | Diverse | 1.07
(0.88–1.30) |
>0.05/<0.0001 | 77 | 9 | 3986
(1813/2173) |
0.512 |
| 24978812 | CD14
(rs2569190) |
GC | 2014 | Dominant | Diverse | 0.99
(0.77–1.26) |
0.144/0.005 | 63 | 12 | 5304
(2968/2336) |
0.4991 |
| 23681795 | CD95L
(rs763110) |
GC | 2013 | Dominant | Diverse | 1.02
(0.83–1.25) |
No/Na | Na | 8 | 4563
(Na/Na) |
0.4696a |
| 23681795 | CD95
(rs1800682) |
GC | 2013 | Dominant | Diverse | 1.00
(0.87–1.15) |
Na/Na | Na | 8 | 3970
(Na/Na) |
0.4543a |
| 21570316 | CDH1
(-616 G>C) |
GC | 2011 | Recessive | Diverse | 1.27
(0.86–1.88) |
Na/Na | Na | 3 | 1962
(565/1397) |
0.2466 |
| 25599647 | CDH1
(rs16260) |
GC | 2015 | AA vs CC | Diverse | 1.19
(0.89–1.58) |
0.323/0.001 | 55 | 22 | 9679
(4218/9679) |
0.2545 |
| 21570316 | CDH1
(+54 T>C) |
GC | 2011 | Recessive | Diverse | 1.00
(0.75–1.34） |
Na/Na | Na | 5 | 2280
(996/1284) |
0.2667 |
| 23775011 | COX-2
(-587 G>A) |
GC | 2013 | A vs G | Diverse | 0.56
(0.19–1.70) |
Na/<0.01 | Na | 3 | 3585
(885/2700) |
0.0313 |
| 24443269 | CYP1A1
(rs4646903) |
GC | 2014 | Dominant | Diverse | 0.950
(0.800–1.128) |
0.017/0.163 | 30.7 | 10 | 3460
(923/2537) |
0.2237 |
| 24443269 | CYP1A1
(rs1048943) |
GC | 2014 | Dominant | Diverse | 0.936
(0.786–1.114) |
0.113/0.876 | 0 | 8 | 4773
(1754/3019) |
0.1577 |
| 27284439 | CYP2E1
(RsaI/PstI) |
GC | 2016 | C2 vs C1 | Diverse | 1.02
(0.86–1.19) |
No/<0.0001 | 61.4 | 26 | 9237
(3727/5510) |
0.1529 |
| 27284439 | CYP2E1
(DraI) |
GC | 2016 | C vs D | Diverse | 1.05
(0.91–1.20) |
No/0.784 | 0 | 6 | 2595
(1225/1370) |
0.1861 |
| 29332452 | DNMT3B
(rs2424913) |
GC | 2017 | T vs C | Asian | 1.25
(0.89–1.76) |
Na/0.81 | 0 | 5 | 3040
(1320/1720) |
0.9706 |
| 28473984 | DNMT1
(rs2228611) |
GC | 2017 | Dominant | Asian | 1.02
(0.83–1.26) |
0.505/0.618 | 0 | 3 | 1469
(652/817) |
0.7173 |
| Continued | |||||||||||