1.
Effect of DM and its derivatives on heat stress-induced HSP70 expression
| |||||||
| Compound | R1 | R2 | IC50 (μM) | Compound | R1 | R2 | IC50 (μM) |
| HeLa cells pretreated with different concentrations of DM or its derivatives were exposed to 42°C for 30 min, and HSP70 expression was examined by qRT-PCR. IC50 was calculated using the SPSS software. | |||||||
| DM |
|
|
4.60 | ||||
| 1 |
|
|
3.75 | 11 |
|
|
15.50 |
| 2 |
|
3.03 | 12 |
|
16.34 | ||
| 3 |
|
9.30 | 13 |
|
12.72 | ||
| 4 |
|
0.81 | 14 |
|
16.31 | ||
| 5 |
|
9.09 | 15 |
|
15.36 | ||
| 6 |
|
|
11.36 | 16 |
|
|
14.00 |
| 7 |
|
12.97 | 17 |
|
12.77 | ||
| 8 |
|
10.99 | 18 |
|
14.15 | ||
| 9 |
|
18.43 | 19 |
|
20.36 | ||
| 10 |
|
11.05 | 20 |
|
4.83 | ||