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. 2019 May;16(2):234–246. doi: 10.20892/j.issn.2095-3941.2018.0284

3.

(A) Colorectal cancer cell lines were plated, rested overnight, drugged and 6 hours later, the cells were either mock irradiated, or irradiated at 4, 8, or 12 Gy. Separation between the control (DMSO) and treated curves indicates radiosensitivity induced by the compound. (B) Human lung fibroblast (HFLA and MRC5) and retinal epithelial (RPE) non-malignant cell lines were drugged in an identical manner and irradiated with 0, 4 or 8 Gy to determine non-cancer cell survival following similar treatment. Data show mean of <italic>n</italic>=3 experiments±SEM.

Clonogenic assays to confirm radiosensitisation of multiple cell lines by PARP inhibitors.