Table 1.

Cohort characteristics

	NPC	Schizophrenia (SZ)
n	20	20
Age, mean ± SD	47.7 ± 9.5	45.4 ± 9.3
Sex, M/F	14/6	14/6
pH, mean ± SD	6.7 ± 0.2	6.5 ± 0.3
PMI, hours ± SD	15.5 ± 5.7	14.5 ± 6.1
Storage time, months ± SD	114.1 ± 42.8	113.6 ± 48.9
Nicotine ATOD, Y/N		14/4
Antipsychotic ATOD, Y/N		18/2
Antidepressant ATOD, Y/N		11/9
Benzodiazepine/VPA ATOD, Y/N		5/15
Asphyxiation, Y/N	3/17	8/12
Hypoxia, Y/N	4/16	4/16
Ischemia, Y/N	0/20	5/15
AHI, Y/N	6/14	12/8

Diagnostic groups showed no significant differences in age (t₃₇ = 0.68, p = 0.50), PMI (t₃₇ = 0.55, p = 0.58), storage time (t₃₇ = 0.14, p = 0.89), pH (t₃₄ = 1.79, p = 0.08), nor in frequency of asphyxiation (X²[1,N = 20] = 3.13, p = 0.08), ischemia (X²[1,N = 20] = 3.66, p = 0.06), hypoxia, or the presence of one or more of these risk variables (AHI; see text) (X²[1,N = 20] = 3.64, p = 0.06). Additional cohort details can be found in Supplementary Table 1

SD standard deviation, PMI postmortem interval, M male, F female, ATOD at time of death, AHI asphyxiation/hypoxia/ischemia (see text)