Table 2.

Univariate tests of association of MAP2-IR with cohort variables

	Δloge(MAP2-IR)	F 1,34	p
Age	−0.03	1.69	0.20
Sex (M = Y, F = N)	0.26	0.22	0.64
PMI	0.01	0.04	0.85
pH	1.96	6.66	0.01
Storage time	0.01	1.81	0.19
		F 1,19	p
Asphyxiation	−0.72	1.7	0.21
Hypoxia	−0.74	1.2	0.29
Ischemia	−1.42	4.2	0.06
AHI	−1.23	7.0	0.02
	Δ% Pairwise loge(MAP2-IR) change (Y group – N group)	t 15 a	p
Nicotine use ATOD	−4.99	0.55	0.59
		t 16	p
Antipsychotic use ATOD	−16.74	1.07	0.30
Antidepressant use ATOD	−2.05	−0.27	0.79
Benzodiazepine/VPA use ATOD	−2.33	−0.28	0.78

Δlog_e(MAP2-IR) is defined as Y–N group for dichotomous variables, or the slope of each continuous variable on MAP2-IR. AHI is a combined variable indicating the presence of asphyxiation, hypoxia, and/or ischemia (see text and Supplementary Table 1)

ATOD at time of death

^aNicotine ATOD status was unknown for one subject