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. 2019 Aug 28;9:12493. doi: 10.1038/s41598-019-48886-8

Table 2.

Total and PF-04957325-sensitive PDE activities measured in granulosa cell homogenates and in mitochondria isolated fractions.

Total PDE activity PF-sensitive PDE activity
(Percentage, %)
Granulosa cells* 2.55 ± 0.08 1.72 ± 0.06 (67,4%)
Isolated mitochondria** 1.10 ± 0.05 0.85 ± 0.05 (77,2%)

Measurements were conducted on two biological replicates in triplicate (n = 2). [PF-04957325] = 30 nM. *Picomoles of cAMP hydrolyzed/min/million cells, **femtomoles of cAMP hydrolyzed/min/fraction.