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. 2019 Aug 28;7(16):e14209. doi: 10.14814/phy2.14209

Figure 2.

Figure 2

The effect of vitamin D status on the innate immune response to a Listeria infection. Two survival studies (top and bottom graph) were performed with two sets of mice with an age range of 16–17 weeks. In the top experiment, 20 vitamin D‐sufficient and 19 vitamin D‐deficient mice were infected with 1.30E+05 CFUs. As negative controls, five vitamin D‐sufficient and three vitamin D‐deficient mice were infected with diluent only (PBS). In the second experimental replicate (bottom), 25 vitamin D‐sufficient and 25 vitamin D‐deficient mice were infected with 7.15E+04 CFUs. As negative controls, five vitamin D‐sufficient and five vitamin D‐deficient mice were infected with diluent only (PBS). In each experiment, mortality was monitored and scored over a 2‐week period. No statistical difference in the survival curves of the D‐deficient mice compared to the D‐sufficient mice was found.