Figure 4.

Tumor Recognition and Cytokine Production of B7-H3-Specific CAR-T Cells In Vitro

(A) Images of co-culture of vehicle and CAR-T cells with autologous GBM cells or GBM cell lines in E:T ratios of 4:1 and 8:1 at 8 h. (B–E) The IFNγ (B: GBM cell lines; C: primary GBM cells) and IL-2 (D: GBM cell lines; E, primary GBM cells) secretion levels of vehicle and CAR-T cells co-cultured with target cells (60,000 T cells to 15,000 tumor cells) for 12 h were measured by ELISA kit (*p < 0.05).