Figure.

Proposed screening algorithm for patients at risk for hepatocellular carcinoma (HCC), based on the American,⁴ European,⁵ Asia-Pacific,⁶ and Japanese⁷ guidelines and expert opinion (*). AFP = α-fetoprotein; CT = computed tomography; HBV = hepatitis B virus; HCV = hepatitis C virus; MRI = magnetic resonance imaging; SVR = sustained virologic response; US = ultrasonography. ^†Situations in which it could be worthwhile to perform cross-sectional imaging include unavailability of experienced personnel, obese patients, patients who are unable to hold their breath, and patients with an excessively nodular liver.