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. 2019 Aug 29;54(2):1801809. doi: 10.1183/13993003.01809-2018

FIGURE 3.

FIGURE 3

Phenotypic features of interleukin (IL)-13+ innate lymphoid cells (ILCs) in severe therapy-resistant asthma (STRA), difficult asthma (DA) and chronic inflammation (CI). Frequency of ILC2s (IL-13+LinnegCD45+) expressing a) CRTH2 and b) CD127 in STRA, DA and CI patient sputum. c) Frequencies of IL-13+ ILCs expressing CRTH2 and CD127 in sputum from STRA patients. Frequency of ILC2s (IL-13+LinnegCD45+) expressing d) both CRTH2 and CD127 and e) neither CRTH2 nor CD127 in STRA, DA and CI patient sputum. Kruskall–Wallis test with a Dunn's post-test, followed by Mann–Whitney test between indicated pairs of groups. *: p<0.05, **: p<0.01, ***: p<0.001. STRA n ≥13, DA n ≥5 and CI n ≥8.