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. 2019 May 6;8(3):379–405. doi: 10.1016/j.jcmgh.2019.04.015

Figure 20.

Figure 20

Reprogramming chief cells survive oxidative stress without inflammatory ROS. Immunostained sections from DMP-777–treated (n = 5) and DMP-777 + sulfasalazine–treated (n = 5) C57Bl/6J mice killed after 10 days of DMP-777 treatment for apoptosis marker CC3 (red), zymogenic granule marker GIF (green), with nuclear counterstain 4′,6-diamidino-2-phenylindole (DAPI) (blue). Scale bars: 100 μm. Magnified inset of chief cell region with arrows indicating CC3 and GIF dual-positive apoptotic chief cells.