Table 2. Adjusted Models for Suicide and Self-harm, by RLS Status.
| Variable | No RLS | RLS |
|---|---|---|
| Cases, No. | 85 | 34 |
| Person-years, No. | 775 879 | 98 435 |
| Incident rate (cases per 1000 person-years) | 0.11 | 0.35 |
| Model, hazard ratio (95% CI) | ||
| Model 1a | 1 [Reference] | 3.55 (2.38-5.30) |
| Model 2b | 1 [Reference] | 2.66 (1.70-4.15) |
Abbreviation: RLS, restless legs syndrome.
a
Model 1 was adjusted for age and sex.
b
Model 2 was adjusted for age, sex, residence (rural or urban), region (South, West, Midwest, Northeast, or unknown), alcohol consumption, and obesity; the presence of chronic obstructive pulmonary disease (surrogate for smoking), diabetes, hypertension, hyperlipidemia, obstructive sleep apnea, depression, insomnia, peripheral neuropathy, rheumatic arthritis, osteoarthritis, chronic kidney disease, iron-deficiency anemia, or Parkinson disease (each, yes or no); and use of antidepressant, antiplatelet, anticoagulant, statin, antihypertensive, and antidiabetic drugs (each, yes or no).