Table 1. Baseline Characteristics of the Transplanted and Discarded Kidneys in the US and French Systemsa.
| Characteristic | Transplanted Kidneys | P Valueb | Discarded Kidneys | P Valueb | ||
|---|---|---|---|---|---|---|
| US Cohort (n=128 102), No. (%) | French Cohort (n=27 252), No. (%) | US Cohort (n=27 987), No. (%) | French Cohort (n=2732), No. (%) | |||
| Age, mean (SD), y | 36.51 (17.02) | 50.91 (17.34) | <.001 | 52.15 (16.39) | 61.58 (17.04) | <.001 |
| Male sex | 77 695 (60.65) | 16 110 (59.11) | <.001 | 14 694 (52.50) | 1710 (62.59) | <.001 |
| Height, mean (SD), cm | 167.76 (20.68) | 169.61 (11.25) | <.001 | 167.28 (19.23) | 167.47 (15.16) | .79 |
| Weight, mean (SD), kg | 77.18 (24.81) | 73.40 (16.16) | <.001 | 81.32 (25.41) | 75.16 (19.20) | <.001 |
| BMI, mean (SD) | 26.68 (6.64) | 25.39 (4.99) | <.001 | 28.44 (7.32) | 26.48 (5.49) | <.001 |
| Hypertension | 31 720 (24.76) | 7919 (29.06) | <.001 | 16 801 (60.03) | 1349 (49.38) | <.001 |
| Diabetes mellitus | 8085 (6.31) | 1844 (6.77) | .005 | 6203 (22.16) | 379 (13.87) | <.001 |
| Hypertension and diabetes | 5495 (4.29) | 1204 (4.42) | .35 | 5243 (18.74) | 310 (11.35) | <.001 |
| Cerebrovascular death | 41 858 (32.68) | 14 871 (54.57) | <.001 | 16 106 (57.55) | 1816 (66.47) | <.001 |
| DCD donor | 15 037 (11.74) | 438 (1.61) | <.001 | 3816 (13.63) | 199 (7.28) | <.001 |
| Creatinine, mean (SD), mg/dL | 1.11 (0.88) | 1.02 (0.61) | <.001 | 1.50 (1.14) | 1.23 (0.80) | <.001 |
| KDRI, mean (SD) | 1.23 (0.41) | 1.50 (0.58) | <.001 | 1.83 (0.56) | 2.03 (0.72) | <.001 |
| KDPI, mean (SD) | 0.45 (0.28) | 0.60 (0.29) | <.001 | 0.77 (0.23) | 0.80 (0.22) | <.001 |
| Positive HCV serology | 2712 (2.12) | 36 (0.13) | <.001 | 2932 (10.48) | 29 (1.06) | <.001 |
| African American donors | 18 003 (14.05) | NAc | NA | 4748 (16.97) | NAc | NA |
Abbreviations: BMI, body mass index (calculated as weight in kilograms divided by height in meters squared); DCD, donors with cardiac death; KDPI, Kidney Donor Risk Profile; KDRI, Kidney Donor Risk Index; NA, not applicable.
Data are based on national registry data from the Organ Procurement and Transplantation Network for the United States and from the national CRISTAL registry in France maintained by the Agence de la Biomédecine, which prospectively collect information on all potential donors and organ transplant recipients along with their outcomes. Inclusion criteria included kidneys from donors with available KDRI data elements. The number of participants with missing data for KDRI was 1525 (1%) for the United States and 1403 (4.5%) for France.
χ2 tests were conducted for the comparison of proportions, and t tests were conducted for the comparison of continuous variables.
Reporting of ethnicity for donors is not permitted per the French regulation data protection rules.