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. 2019 Aug 26;179(11):1519–1527. doi: 10.1001/jamainternmed.2019.2871

Table 4. Outcomes for Treatment vs No Treatment for Asymptomatic Bacteriuria (N = 2733).

Outcomea No. (%) Unadjusted Odds Ratio (95% CI) Unadjusted P Value Adjusted Odds Ratio (95% CI) Adjusted P Value
Antibiotics (n = 2259) No Antibiotics (n = 474)
30-d Postdischarge mortalityb 63 (2.8) 11 (2.3) 1.22 (0.66-2.26) .53 1.34 (0.72-2.49) .35
30-d Postdischarge readmissionb 362 (16.0) 66 (13.9) 1.16 (0.87-1.56) .31 1.29 (0.92-1.81) .14
30-d Postdischarge ED visitb 272 (12.0) 62 (13.1) 0.91 (0.70-1.18) .48 0.90 (0.66-1.24) .52
Discharge to post–acute care facilityb,c 811 (35.9) 102 (21.5) 1.98 (1.58-2.48) <.001 1.19 (0.90-1.57) .22
Clostridioides difficile infectiond 14 (0.6) 2 (0.4) 1.39 (0.41-4.68) .59 0.88 (0.20-3.86) .86
Duration of hospitalization, median (IQR), de 4 (3-6) 3 (2-5) 1.37 (1.28-1.47)f <.001 1.37 (1.28-1.47)f <.001

Abbreviations: ED, emergency department; IQR, interquartile range.

a

Outcomes were adjusted for patient variables found to be significant (P < .05) and associated with treatment in the bivariate and multivariate analysis.

b

Mortality, readmissions, ED visits, and discharge to post–acute care facility were adjusted for age, Charlson Comorbidity Index score, hospitalization in 90 days preceding current admission, admission from nursing home, and insurance type.

c

Long-term acute care hospital, skilled nursing facility, inpatient rehabilitation, and subacute rehabilitation.

d

Infection occurring within 30 days of discharge was adjusted for age, history of antibiotic use and number of antibiotics in previous 90 days, admission from skilled nursing facility, prior hospitalization, proton-pump inhibitor use, immunosuppression, and Charlson Comorbidity Index score.

e

From date of urine testing (either urine culture or urinalysis, whichever was performed first). Adjusted for age, sex, Charlson Comorbidity Index score, prior hospitalization, admission from nursing home, and insurance type.

f

Relative risk given because because duration of hospitalization is a continuous variable.