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. 2019 Aug 28;17:294. doi: 10.1186/s12967-019-2035-8

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© The Author(s) 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 3 — HD-CTC enumeration data for the Kinetics cohort (n = 25). a Change in HD-CTC counts in NSCLC patient samples after entering 1st line therapy. b, c HD-CTC levels before and after entering 1st line therapy where arrows show the direction and magnitude of change and circles represent patients with stable HD-CTC levels. Patients that received bevacizumab treatment are shown with an asterisk. Graphical representation of PFS (b) and OS (c) are provided. Patients with (red) increasing levels, (black) stable levels, and (blue) decreasing levels of HD-CTCs/ml