Table 2.
TCR genes of CD8+CD137+T cells in post-stimulated TIL-F1
| ID | TRAV | TRAJ | CDR3 aa seq. | TRBV | TRBD | TRBJ | CDR3 aa seq. | CD8+CD137+ | |
|---|---|---|---|---|---|---|---|---|---|
| Rank | Freq. (%) | ||||||||
| 1 | TRAV4*01 | TRAJ8*01 | LVGDGKNTGFQKLV | TRBV7–9*03 | TRBD2*01 | TRBJ2–7*01 | ASSLKPGEQY | 1 | 72.09 |
| 2 | TRAV1–2*01 | TRAJ40*01 | AVRAPLLPQEPTNT | TRBV7–9*03 | TRBD2*01 | TRBJ2–7*01 | ASSLKPGEQY | 2 | 11.63 |
| 10 | TRAV13–1*02 | TRAJ22*01 | APLSGSARQLT | TRBV7–9*03 | No Result | TRBJ2–2*01 | ASSLVPGELF | 3 | 9.30 |
| 11 | TRAV8–4*05 | TRAJ40*01 | VVPTTSGTYKYI | TRBV9*01 | TRBD2*02 | TRBJ2–3*01 | ASSTGGGKTDTQY | 4 | 4.65 |
| 12 | TRAV39*01 | TRAJ42*01 | AVEDWGGSQGNLI | TRBV19*01 | TRBD2*01 | TRBJ2–1*01 | ASSPASVGQEQF | 5 | 2.33 |
TCR T-cell receptor, CDR3 Complementarity-determining region, V Variable, D Diversity, J Joining, TRAV T-cell receptor Vα, TRBV T-cell receptor Vβ
*subtypes of TCR genes