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. 2019 Jul 23;23(9):6120–6130. doi: 10.1111/jcmm.14480

Figure 6.

Figure 6

SNHG6 functions as a ceRNA for miR‐181c‐5p to regulate BIM expression. A, Cell viability, B, cell apoptosis and C, caspase‐3 activity were evaluated in cortical neurons transfected with miR‐181c‐5p inhibitor or inhibitor control (N = 3). D, Relative mRNA and protein expression levels of BIM in cortical neurons transfected with pcDNA3.1‐BIM or pcDNA3.1 (N = 3). E, Cell viability, F, cell apoptosis and G, caspase‐3 activity were evaluated in cortical neurons transfected with pcDNA3.1‐BIM or pcDNA3.1 (N = 3). H, Cell viability, I, cell apoptosis and J, caspase‐3 activity were measured in cortical neurons co‐transfected with different siRNAs, miRNAs or plasmids (N = 3). Data were shown as mean ± SD *P < 0.05, **P < 0.01 and ***P < 0.001