Skip to main content
. 2019 Jul 10;23(9):6368–6377. doi: 10.1111/jcmm.14525

Figure 2.

Figure 2

Analysis of cell proliferation and apoptosis. A, An MTT assay showed that IGFBP5 overexpression increased cellular proliferation at day 10; **P < 0.01 and ***P < 0.001 compared with the normal control. B‐D, Flow cytometry and colony formation assays demonstrated that IGFBP5 overexpression could effectively promote NP cell proliferation and inhibit NP cell apoptosis. In contrast, IGFBP5‐shRNA could suppress NP cell proliferation and promote NP cell apoptosis; ***P < 0.001 compared with the normal control. NP, nucleus pulposus