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. 2019 Jul 5;23(9):5836–5845. doi: 10.1111/jcmm.14412

Figure 2.

Figure 2

Depicts the theoretical pathway of Ang‐II‐induced increase in protein degradation. *ROS and *NF‐κB indicate their intracellular pre‐existing forms caused by the oxidative stress pathway depicted in Figure 1. *ROS and *NF‐κB and the arrows originating from them indicate proteins they can interact with and illustrate the feedback loops mentioned above. Other arrows illustrate the up‐regulation or down‐regulation of intracellular proteins by Ang‐II mediated by AT1R