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. 2019 Jul 2;23(9):6271–6282. doi: 10.1111/jcmm.14513

Figure 2.

Figure 2

Down‐regulation of SNAI3‐AS1 inhibits HCC cell proliferation, invasion and migration in vitro. (A) qRT‐PCR analysis of SNAI3‐AS1 expression following transfected HCC cells with SNAI3‐AS1‐shRNAs, **P < 0.01. (B) MTT assays showing that silencing of SNAI3‐AS1 inhibited the proliferation of HCC cells. *P < 0.05. (C) SNAI3‐AS1 knockdown caused a decrease in the clonogenic survival of HCC cells. **P < 0.01. (D) Transwell assays showed SNAI3‐AS1 knockdown reduced the invasion of HCC cells. (scale bars = 50 mm). **P < 0.01. (E,F) Representative images of wound healing assays after SNAI3‐AS1 silencing. *P < 0.05; **P < 0.01. (G) Common cell proliferation‐related proteins expression levels detected by Western blot analysis following SNAI3‐AS1 silencing