Table 1.
Parameters of the patient samples included
| Patients | Karyotype | Total testis volume (ml) | Histological parameters | Sperm (mTESE) | ||||
|---|---|---|---|---|---|---|---|---|
| % SPT | % SPC | % SPG | % SCO | % TS | ||||
| Normal (n = 5) | Not determined | 20.7 (± 11.2) | 66.0 (± 13.4) | 22.2 (± 8.9) | 1.6 (± 1.4) | 0.2 (± 0.4) | 1.4 (± 1.0) | Yes |
| SCO (n = 3) | 46,XY | 8.7 (± 3.8) | 0 | 0 | 0 | 99.0 (± 1.0) | 1.0 (± 1.0) | No |
| KS+ (n = 4) |
1: 48,XXYY 2–4: 47,XXY |
7.8 (± 5.7) | 0.3 (0.5) | 1,75 (± 2.9) | 0 | 73,3 (± 25.6) | 24.3 (± 26.9) | 1, yes; 2–4, no |
| KS− (n = 3) | 1–3: 47,XXY | 2.0 (± 0) | 0 | 0 | 0 | 19.3 (± 11.2) | 80.7 (± 11.2) | 1 no; 2, yes; 3, yes |
Mean values of the testicular volumes per patient group are given as well as the percentage of tubules showing the most advanced stage of germ cell differentiation. Finally, it is indicated whether mTESE samples contained sperm
KS Klinefelter syndrome, + with testicular germ cells, − without testicular germ cells, mTESE microsurgical testicular sperm extraction, Normal testicular tissues with qualitatively normal spermatogenesis, SCO Sertoli cell-only syndrome, SPC spermatocyte, SPG spermatogonia, SPT spermatid, TS tubular shadows