Table 1.
Treatment for two stages.
| Group | First stage | Group | Second stage | ||
|---|---|---|---|---|---|
| Gavage at 9 : 00 am (g/kg·bw) | Gavage at 2 : 00 pm (g/kg·bw) | Gavage at 9 : 00 am (g/kg·bw) | Gavage at 2 : 00 pm (g/kg·bw) | ||
| C | 1% CMC-Na | Pure water | C | 1% CMC-Na | Pure water |
| M | OXO 1.50 + ADE 0.05 | Pure water | M | OXO 1.50 + ADE 0.05 | Pure water |
| A | OXO 1.50 + ADE 0.05 | Allopurinol 0.027 | A | OXO 1.50 + ADE 0.05 | Allopurinol 0.027 |
| AR-L | OXO 1.50 + ADE 0.05 | AR 0.50 | PF-1 | OXO 1.50 + ADE 0.05 | AR 1.00 + RSG 1.00 |
| AR-H | OXO 1.50 + ADE 0.05 | AR 2.00 | PF-2 | OXO 1.50 + ADE 0.05 | AR 2.00 + RSG 1.00 |
| RSG-L | OXO 1.50 + ADE 0.05 | RSG 1.25 | PF-3 | OXO 1.50 + ADE 0.05 | AR 1.00 + RSG 2.00 |
| RSG-H | OXO 1.50 + ADE 0.05 | RSG 5.00 | PF-4 | OXO 1.50 + ADE 0.05 | AR 2.00 + RSG 2.00 |
C, control; M, model; A, allopurinol; AR-L, low-dose of AR; AR-H, high dose of AR; RSG-L, low-dose of RSG; RSG-H, high dose of RSG; PF-1, combination 1; PF-2, combination 2; PF-3, combination 3; PF-4, combination 4; OXO, oteracil potassium; ADE, adenine.