Table 5.
Serum Cr and Ur levels in rats during 45 days in the first stage (n = 10).
| Group | Cr (μmol/L) | Ur (mmol/L) | ||||||
|---|---|---|---|---|---|---|---|---|
| Day 0 | Day 15 | Day 30 | Day 45 | Day 0 | Day 15 | Day 30 | Day 45 | |
| C | 39.52 ± 2.88 | 40.00 ± 4.13 | 42.07 ± 2.59 | 45.78 ± 4.85 | 4.90 ± 0.73 | 4.65 ± 0.70 | 5.03 ± 0.64 | 4.76 ± 0.82 |
| M | 39.41 ± 5.14 | 56.00 ± 2.59▲▲ | 59.47 ± 3.82▲▲ | 62.76 ± 2.93▲▲ | 4.87 ± 0.84 | 6.50 ± 0.86▲▲ | 6.71 ± 0.93▲▲ | 7.63 ± 0.49▲▲ |
| A | 39.39 ± 4.32 | 52.55 ± 3.33 | 59.00 ± 4.48 | 61.40 ± 4.36 | 4.95 ± 0.82 | 5.39 ± 0.66∗∗ | 5.70 ± 0.60∗ | 6.01 ± 0.76∗ |
| AR-L | 39.88 ± 4.87 | 57.01 ± 7.38 | 59.93 ± 5.07 | 64.55 ± 7.56 | 4.70 ± 0.79 | 6.62 ± 0.76 | 6.43 ± 0.72 | 7.12 ± 1.13 |
| AR-H | 38.56 ± 3.82 | 56.79 ± 5.03 | 59.19 ± 4.24 | 64.91 ± 5.88 | 4.78 ± 0.60 | 6.45 ± 0.93 | 6.66 ± 1.34 | 7.34 ± 2.20 |
| RSG-L | 37.70 ± 2.56 | 56.21 ± 5.04 | 58.91 ± 5.01 | 63.47 ± 7.61 | 4.68 ± 0.58 | 6.47 ± 0.88 | 6.05 ± 1.24 | 7.35 ± 1.49 |
| RSG-H | 38.89 ± 3.31 | 55.11 ± 7.42 | 53.92 ± 3.08∗∗ | 52.43 ± 9.65∗∗ | 4.74 ± 0.62 | 6.52 ± 0.69 | 5.76 ± 0.84∗ | 6.13 ± 1.27∗ |
C, control; M, model; A, allopurinol; AR-L, low dose of AR; AR-H, high dose of AR; RSG-L, low dose of RSG; RSG-H, high dose of RSG. ▲▲Significantly different from those of the control group at the level of P < 0.01. ∗ and ∗∗ indicate values significantly different from those of the model group at the levels of P < 0.05 and P < 0.01, respectively.