Table 9.
Serum Cr and Ur levels of rats with different treatment during 45 days in the second stage (n = 10).
| Group | Cr (μmol/L) | Ur (mmol/L) | ||||||
|---|---|---|---|---|---|---|---|---|
| Day 0 | Day 15 | Day 30 | Day 45 | Day 0 | Day 15 | Day 30 | Day 45 | |
| C | 34.78 ± 3.27 | 34.36 ± 2.43 | 37.46 ± 2.99 | 39.23 ± 7.40 | 4.17 ± 0.80 | 3.91 ± 0.74 | 4.32 ± 0.64 | 4.83 ± 0.88 |
| M | 35.57 ± 4.31 | 46.07 ± 1.51▲▲ | 54.67 ± 5.01▲▲ | 61.57 ± 9.69▲▲ | 4.31 ± 0.49 | 5.23 ± 0.60▲▲ | 7.14 ± 1.19▲▲ | 10.20 ± 1.55▲▲ |
| A | 34.01 ± 2.24 | 34.06 ± 1.54∗∗ | 41.76 ± 3.67∗∗ | 50.98 ± 11.22∗∗ | 4.13 ± 0.66 | 4.49 ± 0.71∗∗ | 5.68 ± 0.82∗∗ | 7.05 ± 1.23∗∗ |
| PF-1 | 32.78 ± 3.20 | 44.57 ± 1.82 | 52.84 ± 3.18 | 55.42 ± 12.61 | 3.85 ± 0.62 | 4.59 ± 0.47∗ | 6.84 ± 0.57 | 8.34 ± 2.54∗∗ |
| PF-2 | 34.46 ± 5.23 | 46.46 ± 4.34 | 52.01 ± 3.20∗ | 50.60 ± 10.16∗ | 4.31 ± 0.90 | 4.95 ± 1.03 | 6.54 ± 0.75∗ | 8.36 ± 1.17∗∗ |
| PF-3 | 33.52 ± 3.64 | 44.93 ± 3.28 | 49.96 ± 2.43∗∗ | 48.94 ± 14.55∗∗ | 4.12 ± 0.72 | 4.67 ± 0.68∗ | 6.14 ± 0.78∗∗ | 8.20 ± 2.31∗∗ |
| PF-4 | 32.66 ± 2.54 | 45.76 ± 2.09 | 51.33 ± 2.75∗ | 48.52 ± 12.91∗∗ | 3.87 ± 0.73 | 4.73 ± 0.73 | 6.18 ± 0.76∗∗ | 7.85 ± 1.44∗∗ |
C, control; M, model; A, allopurinol; PF-1, combination 1; PF-2, combination 2; PF-3, combination 3; PF-4, combination 4. ▲▲Significantly different from those of control group at the level of P < 0.01. ∗ and ∗∗ indicate values significantly different from those of model group at the levels of P < 0.05 and P < 0.01, respectively.