Table 2.
Top 5% functional annotation of upregulated genes of the embryos on Day 12
| Category description | Gene Counts | Fold Enrichment | FDR | P Value |
|---|---|---|---|---|
| Prostatic bud formation | 7 | 7.82 | 0.12 | 0.0001 |
| Metalloendopeptidase inhibitor activity | 10 | 6.21 | 0.01 | 0.0000 |
| Chemorepellent activity | 14 | 5.15 | 0.00 | 0.0000 |
| Lateral sprouting from an epithelium | 8 | 6.70 | 0.10 | 0.0000 |
| Collagen-activated signaling pathway | 6 | 7.54 | 0.84 | 0.0004 |
| Glomerulus vasculature development | 12 | 5.24 | 0.01 | 0.0000 |
| Laminin complex | 6 | 7.16 | 0.82 | 0.0005 |
| Cardiac septum morphogenesis | 25 | 3.99 | 0.00 | 0.0000 |
| Positive regulation of extracellular matrix organization | 10 | 5.58 | 0.04 | 0.0000 |
| Negative chemotaxis | 17 | 4.17 | 0.00 | 0.0000 |
| Morphogenesis of an epithelial bud | 8 | 6.18 | 0.19 | 0.0001 |
| Glomerulus development | 24 | 3.83 | 0.00 | 0.0000 |
| Creatine metabolic process | 7 | 6.39 | 0.57 | 0.0003 |
| Cardiac septum development | 34 | 3.56 | 0.00 | 0.0000 |
| Positive regulation of epithelial cell migration | 37 | 3.54 | 0.00 | 0.0000 |
| Ventricular septum development | 22 | 3.51 | 0.00 | 0.0000 |
| Renal system vasculature development | 12 | 4.82 | 0.02 | 0.0000 |
| Kidney vasculature development | 12 | 4.82 | 0.02 | 0.0000 |
| Kidney morphogenesis | 32 | 3.42 | 0.00 | 0.0000 |
| Basement membrane | 34 | 3.42 | 0.00 | 0.0000 |
| Nephron development | 46 | 3.35 | 0.00 | 0.0000 |
| Cardiac chamber morphogenesis | 39 | 3.32 | 0.00 | 0.0000 |
| Renal tubule development | 31 | 3.28 | 0.00 | 0.0000 |
| Nephron tubule development | 30 | 3.28 | 0.00 | 0.0000 |
| Renal tubule morphogenesis | 25 | 3.26 | 0.00 | 0.0000 |
| Nephron morphogenesis | 25 | 3.22 | 0.00 | 0.0000 |
| Embryonic skeletal joint development | 8 | 5.74 | 0.35 | 0.0002 |
| Positive regulation of ossification | 27 | 3.19 | 0.00 | 0.0000 |
| Mesonephros development | 32 | 3.12 | 0.00 | 0.0000 |
| Smooth muscle cell migration | 20 | 3.53 | 0.00 | 0.0000 |
| Ureteric bud development | 30 | 3.11 | 0.00 | 0.0000 |
| Extracellular matrix disassembly | 27 | 3.08 | 0.00 | 0.0000 |
| Mesonephric epithelium development | 30 | 3.08 | 0.00 | 0.0000 |
| Mesonephric tubule development | 30 | 3.08 | 0.00 | 0.0000 |
| Cardiac chamber development | 47 | 3.05 | 0.00 | 0.0000 |
| Kidney epithelium development | 43 | 3.02 | 0.00 | 0.0000 |
| Nephron epithelium morphogenesis | 24 | 3.17 | 0.00 | 0.0000 |