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. 2019 Aug 28;19:851. doi: 10.1186/s12885-019-6041-2

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 2 — The SOX signature represents an oncogenic dedifferentiation phenotype. a The normalized expressions of liver cancer dedifferentiation markers and liver progenitor cell markers in HCC patients with different SOX signature score. b The normalized expressions of hepatocyte terminal differentiation markers in HCC patients with different SOX signature score. One-way ANOVA test. P value less than 0.05 was considered statistically significant. The figures were generated using GraphPad Prism 5