Table 4.
Measurements from infants who were randomized to resuscitation with an intact cord (intervention) or after early cord clamping (control), only including those resuscitated with bag and mask
| Cord Clamping Group, Mean (SD) | Difference (95% CI) | P-valuea | ||
|---|---|---|---|---|
| Intact cord > 3 min | Early < 1 min) | |||
| Readings from pulse oximeter | (n = 72) | (n = 45) | ||
| Saturation at 1 min (%) | 73.7 (8.8) | 62.6 (5.0) | 11.1 (8.2 to 13.9) | <.001 |
| Saturation at 5 min (%) | 85.6 (8.1) | 76.1 (3.9) | 9.4 (6.9 to 12.0) | <.001 |
| Saturation at 10 min (%) | 91.9 (7.9) | 85.1 (2.8) | 6.8 (4.4 to 9.3) | <.001 |
| Heart rate at 1 min | 106 (3) | 115 (5) | −10 (−11 to −8) | <.001 |
| Heart rate at 5 min | 124 (4) | 134 (4) | −10 (− 11 to −8) | <.001 |
| Heart rate at 10 min | 136 (2) | 136 (2) | 1 (0 to 2) | .05 |
| Apgar score | (n = 74) | (n = 48) | ||
| Apgar at 1 min | 5.0 (1.1) | 3.8 (1.1) | 1.2 (0.8 to 1.6) | < 0.001 |
| Apgar at 5 min | 6.7 (0.9) | 6.0 (1.3) | 0.7 (0.3 to 1.1) | 0.001 |
| Apgar at 10 min | 9.2 (1.2) | 8.3 (1.8) | 0.9 (0.3 to 1.5) | 0.005 |
| Timed events, Median (interquartile range) | (n = 74) | (n = 48) | ||
| Time of start of resuscitation (sec) | 48 (30 to 71) | 43 (23 to 57) | . 06b | |
| Time of first cry/breath (sec) | 38 (34 to 45) | 48 (45 to 62) | <.001b | |
| Time of regular breathing (sec)c | 78 (67 to 155) | 356 (98 to 389) | <.001b | |
| Time to cord clamping (sec) | 187 (42 to 195) | 25 (11 to 40) | <.001 b | |
aCalculated using an unpaired 2-tailed t test
bCalculated using Mann Whitney U test
cIntact cord group n = 72 and the early group n = 45