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. 2019 Aug 23;2(8):e199951. doi: 10.1001/jamanetworkopen.2019.9951

Table 2. Risk Factor Subset Analysis.

Factor Studies, No. No. Infected/Total No. (%) Odds Ratio (95% CI) P Value I2, %
Smoking status 9 246/2562 (9.6)
Smoker 121/801 (15.1) 1.99 (1.51-2.62) <.001 0
Nonsmoker 125/1761 (7.6) 1 [Reference]
Diabetes status 10 237/2826 (8.4)
With diabetes 35/244 (14.3) 1.70 (1.15-2.53) .008 0
Without diabetes 202/2582 (7.8) 1 [Reference]
Sex 9 206/2765 (7.5)
Men 158/1790 (8.8) 1.98 (1.41-2.78) <.001 14.51
Women 48/975 (4.9) 1 [Reference]
Compartment syndrome status 7 193/1636 (11.8)
With compartment syndrome 44/130 (33.8) 4.22 (2.80-6.37) <.001 0
Without compartment syndrome 149/1506 (9.9) 1 [Reference]
Fracture type 11 232/2225 (10.4)
Open 61/253 (24.1) 3.45 (2.45-4.85) <.001 16.71
Closed 171/1972 (8.7) 1 [Reference]