Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
The rs2240183 C allele increased the transcriptional activity. A, Schematic representation of the plasmid construction of TUG1 promoter. A 3396 bp promoter sequence of TUG1 containing the rs2240183 C or T allele (from −3210 to +186bp) was cloned into a pGL3 basic vector. TSS, transcriptional start site. B, The plasmids were transfected into HEK293 cells and luciferase activity was measured 48 h after transfection (**P < 0.01)
