Table 1.
The medically biochemical data of VPA‐treated epileptic patients
| Parameters | Pooled data | Clinical ranges |
|---|---|---|
| Age (y) | 51.0 ± 4.9 | — |
| Sex (M/F) | 2/1 | — |
| K (mmol/L) | 3.95 ± 0.48 | 3.5‐5.5 |
| Na (mmol/L) | 139.17 ± 4.73 | 135‐145 |
| Cl (mmol/L) | 101.80 ± 5.55 | 96‐108 |
| Ca (mmol/L) | 2.28 ± 0.12 | 2.1‐2.6 |
| Mg (mmol/L) | 0.91 ± 0.22 | 0.67‐1.04 |
| P (mmol/L) | 1.27 ± 0.2 | 0.96‐1.62 |
| GLU (mmol/L) | 7.19 ± 1.72 | 3.89‐6.11 |
| AMY (U/L) | 139 ± 48.54 | <220 |
| Urea (mmol/L) | 3.71 ± 1.66 | 1.7‐8.3 |
| Cr (μmol/L) | 65 ± 18.36 | 44‐98 |
| UA (μmol/L) | 335.67 ± 94.77 | 150‐420 |
| HCO3 (mmol/L) | 25.13 ± 1.3 | 22‐28 |
| CYS‐C (mg/L) | 0.95 ± 0.26 | 0.55‐1.55 |
| β2‐MG (mg/L) | 1.46 ± 0.61 | 0‐3 |
| CHO (mmol/L) | 4.76 ± 0.74 | 3.12‐6.24 |
| TG (mmol/L) | 3.19 ± 0.21 | <1.71 |
| HDL‐C (mmol/L) | 0.94 ± 0.23 | 0.91‐1.56 |
| LDL‐C (mmol/L) | 2.89 ± 0.78 | <3.5 |
| Apo A1 (g/L) | 0.99 ± 0.29 | 1‐1.6 |
| Apo B (g/L) | 0.97 ± 0.09 | 0.6‐1.1 |
| HsCRP (mg/L) | 2.52 ± 2.27 | <3 |
| CK‐NAC (U/L) | 41 ± 18.33 | 26‐174 |
| CK‐MB (U/L) | 17 ± 11.36 | <24 |
| LDH‐L (U/L) | 184 ± 40.93 | 115‐220 |
| α‐HBDH (U/L) | 173.67 ± 54.86 | 72‐182 |
| TBIL (μmol/L) | 5.07 ± 1.75 | 3.4‐20.6 |
| DBIL (μmol/L) | 1.93 ± 0.85 | <8.6 |
| IBIL (μmol/L) | 3.13 ± 0.9 | <5.4 |
| ALT (U/L) | 12.33 ± 1.15 | <35 |
| AST (U/L) | 16 ± 4.36 | <40 |
| ALP (U/L) | 88 ± 6.24 | 40‐150 |
| GGT (U/L) | 50.33 ± 32.87 | <32 |
| TBA (μmol/L) | 11.23 ± 5.91 | <10 |
| 5‐NT (U/L) | 2.23 ± 1 | <10 |
| TP (g/L) | 64.73 ± 8.41 | 65‐85 |
| ALB (g/L) | 40.43 ± 1.92 | 40‐55 |
| GLB (g/L) | 24.30 ± 6.58 | <45 |
| AFP (ng/mL) | 2.50 ± 1.47 | <25 |
| VPA (μg/mL) | 54.13 ± 17.07 | 50‐100 |
Abbreviations: 5‐NT, 5‐nucleotide enzyme; AFP, alpha fetoprotein; ALB, albumin; ALP, alkaline phosphatase; ALT, glutamic‐pyruvic transaminase; AMY, amylase; Apo A1, apolipoprotein A1; Apo B, apolipoprotein B; AST, glutamic‐oxaloacetic transaminase; CHO, total cholesterol; CK‐MB, creatine kinase, MB form; CK‐NAC, creatine kinase; Cr, creatinine; CYS‐C, cystatin c; DBIL, direct bilirubin; dehydrogenase; F, female; GGT, glutathione transpeptidase; GLP, globulin; GLU, glucose in urine; HDL‐C, high‐density lipoprotein; HsCRP, hypersensitive C‐reactive protein; IBIL, indirect bilirubin; LDH‐L, lactate dehydrogenase L; LDL‐C, low‐density lipoprotein; M, male; TBA total, bile acids; TBIL, total bilirubin; TG, triglyceride; TP, total protein; UA, uric acid; VPA, valproate acid; α‐HBDH, α‐hydroxybutyrate; β2‐MG, β2‐microglobulin.