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. 2019 Aug 22;10:1891. doi: 10.3389/fpsyg.2019.01891

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Copyright © 2019 Walleczek and von Stillfried.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Illustration of a typical true-experiment when the test subject is present during the whole 20-min session. A segment of the real-time recording of DS-light-interference intensity by the photo-imaging camera is shown in terms of the primary outcome variable Y as defined in the pre-specified Matlab software script (for details, see Section “Materials and Methods”). The sequence of test categories or trials, i.e., X/O, O/O, X/X, and O/X, is generated randomly and is presented to the test subject in the form of computer-assisted instructions. The four possible test trials to be performed by the subject are marked in the Figure (X/O, O/O, X/X, and O/X; see also Section “Three Additional Control Test Categories”); each of the four test categories is repeated randomly five times during the 20-min session, yielding a total of 20 test trials per 20-min session. The 30-s epoch marked by the label O represents the control, i.e., “relax,” test condition. The test condition “concentrate” is represented by the 30-s epoch that is marked by the label X. After the completion of each individual test trial (i.e., 2 × 30-s epochs), a 10-s delay was added before the start of the next trial (see the short black sectors). Importantly, either before or after the 20-min true-experiment, the paired 20-min sham-experiment is performed. For more details see the main text in Section “Insertion of the AMP Into the Radin DS-Experiment.” For more information about the “relax” (O) and “concentrate” (X) test conditions, see the description in the legend to Table 1.