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. Author manuscript; available in PMC: 2020 Oct 1.
Published in final edited form as: Neurobiol Dis. 2019 Jun 22;130:104502. doi: 10.1016/j.nbd.2019.104502

Figure 1. Mitochondrial biogenesis proteins are reduced in HAND brains on ART.

Figure 1

(A) Immunoblot of HAND donor frontal lobe lysates with antibodies specific for PGC-1α and TFAM, normalized to ACTB. (B and C) Quantification of PGC-1α and TFAM band intensity stratified by HAND diagnosis. (D and E) Quantification of PGC-1α and TFAM band intensity stratified by CN vs. HAND. Statistical significance was determined by an unpaired t test. *, p<0.05, **, p<0.01.