Table 3.
Cox Proportional Hazards Model
| Variable | HR (95% CI) | p Value |
|---|---|---|
| Sex | ||
| Male | Ref | - |
| Female | 0.90 (0.77–1.06) | 0.199 |
| Age, years | ||
| <20 | Ref | - |
| 20–39 | 1.39 (0.93–2.09) | 0.112 |
| 40–59 | 3.29 (1.80–6.05) | <0.001 |
| 60–79 | 4.53 (2.48–8.29) | <0.001 |
| 80+ | 8.50 (4.44–16.3) | <0.001 |
| Race | ||
| Hispanic | 0.83 (0.60–1.15) | 0.276 |
| Non-Hispanic white | Ref | - |
| Non-Hispanic black | 1.20 (0.93–1.53) | 0.160 |
| Other | 1.24 (0.86–1.78) | 0.256 |
| Charleson-Deyo score | ||
| 0 | Ref | - |
| 1 | 1.51 (1.24–1.84) | <0.001 |
| 2+ | 1.85 (1.35–2.54) | <0.001 |
| Histology | ||
| Hemangiosarcoma | Ref | - |
| Sarcoma, NOS | 0.86 (0.68–1.08) | 0.186 |
| Leiomyosarcoma | 0.48 (0.35–0.66) | <0.001 |
| Synovial sarcoma | 0.88 (0.67–1.16) | 0.367 |
| Malignant peripheral nerve sheath tumor | 0.76 (0.51–1.13) | 0.179 |
| Other | 0.59 (0.47–0.75) | <0.001 |
| Tumor Size | ||
| ≤10 cm | Ref | - |
| >10 cm | 1.16 (0.94–1.44) | 0.164 |
| Unknown | 1.29 (1.07–1.56) | 0.007 |
| Grade | ||
| Well-differentiated | Ref | - |
| Moderately differentiated | 1.59 (0.81–3.1) | 0.177 |
| Poorly differentiated | 2.58 (1.51–4.41) | 0.001 |
| Undifferentiated | 3.24 (1.88–5.58) | <0.001 |
| Unknown | 2.63 (1.55–4.44) | <0.001 |
| Metastases | 1.60 (1.30–1.97) | <0.001 |
| Treatment | ||
| Surgery and radiation | 0.24 (0.16–0.36) | <0.001 |
| Surgery only | 0.36 (0.27–0.47) | <0.001 |
| Surgery and chemoradiation | 0.30 (0.21–0.44) | <0.001 |
| Surgery and chemotherapy | 0.33 (0.25–0.43) | <0.001 |
| Radiation and chemotherapy | 0.49 (0.39–0.61) | <0.001 |
| No treatment | Ref | - |
| Facility location | ||
| New England (CT, MA, ME, NH, RI, VT) | Ref | - |
| Middle Atlantic (NJ, NY, PA) | 0.51 (0.32–0.82) | 0.006 |
| South Atlantic (DC, DE, FL, GA, MD, NC, SC, VA, WV) | 0.49 (0.30–0.79) | 0.004 |
| East North Central (IL, IN, MI, OH, WI) | 0.55 (0.34–0.90) | 0.017 |
| East South Central (AL, KY, MS, TN) | 0.57 (0.32–1.03) | 0.063 |
| West North Central (IA, KS, MN, MO, ND, NE, SD) | 0.60 (0.35–1.01) | 0.056 |
| West South Central (AR, LA, OK, TX) | 0.41 (0.24–0.70) | 0.001 |
| Mountain (AZ, CO, ID, MT, NM, NV, UT, WY) | 0.52 (0.29–0.93) | 0.028 |
| Pacific (AK, CA, HI, OR, WA) | 0.56 (0.34–0.94) | 0.027 |
| Urban (versus non-urban) | 0.76 (0.35–1.64) | 0.480 |
| Academic (versus non-academic) | 0.89 (0.73–1.09) | 0.249 |
| Medicaid or uninsured | 1.26 (1.00–1.62) | 0.050 |
| Income | ||
| <$38,000 | Ref | - |
| $38,000-$47,999 | 1.14 (0.87–1.49) | 0.345 |
| $48,000-$62,999 | 0.97 (0.73–1.29) | 0.826 |
| ≥$63,000 | 0.98 (0.73–1.33) | 0.917 |
| Education quartile | ||
| Lowest | Ref | - |
| Second | 0.97 (0.75–1.25) | 0.809 |
| Third | 1.05 (0.80–1.38) | 0.740 |
| Highest | 1.01 (0.73–1.38) | 0.967 |
CI = confidence interval; HR = hazard ratio; NOS = not otherwise specified; Ref = reference.