Table 3.
OR (95% CI) | |||
---|---|---|---|
Characteristic | Unadjusted | Adjusted | p Valuea |
Sex (male) | 0.92 (0.86–0.98) | 0.98 (0.91–1.06) | 0.637 |
Age (years) | |||
≤55 | Referent | ||
56–65 | 1.02 (0.91–1.15) | 1.04 (0.92–1.18) | 0.504 |
66–75 | 1.13 (1.01–1.25) | 1.16 (1.02–1.33) | 0.024 |
>75 | 1.13 (1.00–1.27) | 1.20 (1.03–1.41) | 0.022 |
Race | |||
White | Referent | ||
Black | 1.19 (1.07–1.33) | 1.14 (0.94–1.39) | 0.191 |
Other | 1.52 (1.35–1.71) | 1.44 (0.92–2.26) | 0.115 |
Population area | |||
Nonmetropolitan or unspecified | Referent | ||
Metropolitan | 1.37 (1.25–1.50) | 1.29 (1.05–1.58) | 0.013 |
Comorbidities | |||
COPD | 1.07 (1.00–1.15) | 1.14 (1.02–1.28) | 0.018 |
Congestive heart failure | 1.03 (0.84–1.26) | 1.02 (0.82–1.26) | 0.880 |
Diabetes | 1.09 (1.00–1.19) | 1.05 (0.95–1.16) | 0.347 |
Hypertension | 1.11 (1.04–1.19) | 1.05 (0.94–1.16) | 0.395 |
Peripheral vascular disease | 1.18 (1.03–1.35) | 1.18 (1.03–1.35) | 0.016 |
Tumor size | |||
<3.0 cm | Referent | ||
3.0–4.9 cm | 0.83 (0.77–0.90) | 0.87 (0.75–1.01) | 0.061 |
5.0–6.9 cm | 0.55 (0.48–0.63) | 0.63 (0.53–0.76) | <0.001 |
≥7.0 cm | 0.38 (0.31–0.47) | 0.46 (0.35–0.60) | <0.001 |
Tumor location | |||
Lower lobe | Referent | ||
Middle lobe | 1.05 (0.92–1.21) | 0.95 (0.79–1.14) | 0.591 |
Upper lobe | 0.88 (0.82–0.95) | 0.85 (0.77–0.94) | 0.001 |
Other or unspecified | 0.66 (0.53–0.83) | 0.70 (0.54–0.92) | 0.001 |
Histology | |||
Adenocarcinoma | Referent | ||
Squamous | 0.84 (0.78–0.91) | 0.91 (0.83–1.00) | 0.049 |
Carcinoid | 1.09 (0.95–1.25) | 1.03 (0.89–1.20) | 0.652 |
Other | 0.80 (0.70–0.92) | 0.91 (0.78–1.07) | 0.255 |
AJCC stage | |||
IA | Referent | ||
IB | 0.88 (0.81–0.95) | 0.98 (0.88–1.09) | 0.724 |
IIA | 0.70 (0.63–0.78) | 0.85 (0.75–0.96) | 0.009 |
IIB | 0.59 (0.52–0.67) | 0.81 (0.69–0.96) | 0.015 |
IIIA | 0.66 (0.59–0.75) | 0.80 (0.69–0.93) | 0.004 |
Hospital type | |||
Community/other | Referent | ||
Academic or NCI designated | 1.77 (1.65–1.89) | 1.55 (1.03–2.33) | 0.037 |
Hospital volume | |||
Quartile 1, 2, and 3 | Referent | ||
Quartile 4 (highest volume) | 1.74 (1.61–1.87) | 1.48 (1.03–2.12) | 0.033 |
P value from multivariable regression model.
AJCC = American Joint Committee on Cancer; CI = confidence interval; COPD = chronic obstructive pulmonary disease; NCI = National Cancer Institute; OR = odds ratio.