Table 4.

Changes in Antithrombotic Therapy Pre- and Post-intervention.^a

Change in Therapy, Number of Patients (% Within Group)	Baseline (N = 101)	Discharge (N = 82)	P Value
Upgrade in therapyb
Nil therapy to warfarin	13 (6.6)	7 (3.5)	.02b
Aspirin/clopidogrel to warfarin	36 (18.4)	34 (17.4)
Nil to aspirin/clopidogrel	11 (5.6)	5 (2.5)
Total	60 (30.8)	46 (23.5)
Downgrade in therapyc
Warfarin to aspirin	37 (19)	32 (16.4)	.29
Total	37 (19)	32 (16.4)
Sidesteppingd
Aspirin to clopidogrel	2 (1)	2 (1)	.5
Clopidogrel to aspirin	2 (1)	2 (1)
Total	4 (2)	4 (2)

^aN = 195.

^bPatients requiring a change from less effective to more effective stroke prevention therapy (eg, from nil therapy to anticoagulant or antiplatelet therapy or from antiplatelet therapy to anticoagulant therapy).

^cPatients requiring change to less effective, albeit safer, therapy (eg, from anticoagulant to antiplatelet or from antiplatelet or anticoagulant to nil therapy).

^dPatients requiring change within the same class of treatment (eg, changing from one anticoagulant to another anticoagulant or from one antiplatelet to another antiplatelet).