Table 3.

Accuracy for High- Versus Low-Risk Categories to Predict Occult Cancer, According to Sex.

	Male		Female
Variable	(246/2644)		(198/2974)
Occult Cancer/Patients		95% CI		95% CI
C-statistic	0.64	0.60-0.68	0.61	0.57-0.65
Sensitivity	60.6%	54.3%-66.5%	27.3%	21.5%-33.9%
Specificity	62.0%	60.1%-63.8%	81.8%	80.3%-83.2%
Positive predictive value	12.9%	11.1%-15.0%	9.7%	7.5%-12.4%
Negative predictive value	94.4%	93.2%-95.4%	94.0%	93.0%-94.9%
Odds ratio diagnosis	2.50	1.91-3.27	1.69	1.22-2.34
Positive likelihood ratio	1.59	1.42-1.78	1.50	1.18-1.91
Negative likelihood ratio	0.64	0.54-0.75	0.89	0.81-0.98
Pretest probability (prevalence)	8.5%	7.5%-9.6%	6.7%	5.8%-7.6%
Posttest probability high risk (Bayes)	12.9%	11.1%-14.9%	9.7%	7.5%-12.5%
Number needed to screen	14	11-20	28	16-94

Abbreviation: CI, confidence interval.