Table 1.

Heparin Nomograms Based on aPTT and Anti-Xa Concentrations.

Nomogram	Initial Bolus Dose (Maximum)	Initial Infusion Dose (Maximum)	Goal aPTT (Seconds)	Goal Anti-Xa Concentration (U/mL)
DVT/PE	80 U/kg (10 000 U)	18 U/kg/h (1600 U/h)	68-106	0.3-0.7
UA/NSTEMI	60 U/kg (4000 U)	12 U/kg/h (1000 U/h)	68-96	0.3-0.6
Afib/Post-Op	60 U/kg (10 000 U)	10 U/kg/h (1600 U/h)	68-82	0.3-0.45
Stroke/EP/VAD/high-risk bleed	NA	8 U/kg/h (1600 U/h)	59-72	0.25-0.35

Abbreviations: Afib, atrial fibrillation; aPTT, activated partial thromboplastin time; DVT/PE, deep vein thrombosis/pulmonary embolism; EP, electrophysiology; Post-Op, postoperative; UA/NSTEMI, unstable angina/non-ST-segment elevation myocardial infarction; VAD, ventricular assist device.