Absolute changes in EXTEM clotting time and FIBTEM maximum clot firmness after the
addition of increasing doses of factor XIII (+20%, +40%, and +60%) in blood samples
from cardiac surgery patients (n = 9), alone or in combination with a fixed dose of
fibrinogen or platelets. See Methods section for details. †
P < .05, ††
P < .01, †††
P < .001, relative to baseline. #
P < .05, ##
P < .01 compared to another dose of FXIII (within
treatment). Outliers (values more than 1.5 times the interquartile range away from
the lower or upper quartile) are shown with circles.