Figure 2.

Absolute changes in EXTEM clotting time and FIBTEM maximum clot firmness after the addition of increasing doses of factor XIII (+20%, +40%, and +60%) in blood samples from scoliosis surgery patients (n = 10), alone or in combination with a fixed dose of fibrinogen or platelets. See Methods section for details. ^† P <.05, ^†† P <.01, ^††† P < .001, relative to baseline. ^### P <.001 compared to another dose of FXIII (within treatment). Outliers are denoted with circles and extreme values with stars. Outliers and extreme values are values more than 1.5 and 3 times the interquartile range, respectively, away from the lower or upper quartile.