Table 2.
Results of Clot Formation Analyses of Blood Samples From Cardiac and Scoliosis Surgery Patients.a
| Sample | Cardiac Surgery Patients (n = 9) | Scoliosis Surgery Patients (n = 10) | ||||
|---|---|---|---|---|---|---|
| EXTEM Clotting Time (s) | EXTEM Maximum Clot Firmness (mm) | FIBTEM Maximum Clot Firmness (mm) | EXTEM Clotting Time (s) | EXTEM Maximum Clot Firmness (mm) | FIBTEM Maximum Clot Firmness (mm) | |
| Baseline | 78 (69-88) | 55 (52-58) | 12 (9.2-15) | 69 (61-78) | 55 (51-58) | 8.4 (6.6-10) |
| FXIII low | 76 (67-85) | 56 (53-58) | 14 (11-16) | 63 (58-69) | 55 (52-58) | 8.5 (6.8-10) |
| FXIII medium | 73 (66-81) | 56 (53-58) | 14 (12-16) | 64 (56-71) | 55 (52-58) | 8.9 (7.5-10) |
| FXIII high | 70 (62-78) | 57 (54-60) | 15 (12-17) | 62 (55-69) | 55 (52-58) | 9.6 (7.9-11) |
| FXIII low + fibrinogen | 68 (60-77) | 62 (60-64) | 25 (24-27) | 53 (47-58) | 62 (59-64) | 19 (17-21) |
| FXIII medium + fibrinogen | 68 (60-76) | 61 (59-64) | 26 (24-28) | 52 (47-56) | 62 (59-65) | 20 (18-22) |
| FXIII high + fibrinogen | 67 (61-73) | 63 (61-65) | 28 (26-30) | 54 (49-58) | 62 (59-65) | 21 (19-24) |
| FXIII low + platelets | 66 (59-73) | 63 (60-65) | 14 (12-16) | 58 (52-64) | 61 (58-64) | 10 (8.5-12) |
| FXIII medium + platelets | 62 (55-70) | 63 (61-65) | 15 (13-17) | 57 (51-62) | 61 (58-64) | 11 (8.8-13) |
| FXIII high + platelets | 64 (55-73) | 63 (61-65) | 15 (13-18) | 56 (50-61) | 61 (59-64) | 11 (9.0-13) |
aThe blood samples were either supplemented with factor XIII (FXIII; +20%, +40%, and +60%), alone or in combination with a fixed dose of fibrinogen or platelets. Values are presented as mean and 95% confidence interval.