Table 2.
Relationship Functional Levels of Factors VII, IX, and X to INR in Warfarin-Treated Patients and Patients With SAC.
| INR | Warfarin-Treated Patients | Patients With SAC | |||||||
|---|---|---|---|---|---|---|---|---|---|
| Mean | Median | SEM | n | Mean | Median | SEM | n | ||
| Factor VII, functional (%) | <1.5 | 59.0 | 59.3 | 3.1 | 26 | 101.7 | 104.3 | 3.4 | 46 |
| 1.5-1.9 | 48.7 | 46.9 | 3.0 | 29 | 72.2 | 72.8 | 4.1 | 19 | |
| 2-2.9 | 37.0 | 34.8 | 2.1 | 33 | 93.2 | 85.9 | 16.1 | 10 | |
| ≥3 | 20.2 | 19.6 | 3.5 | 12 | 88.4 | 112.5 | 28.6 | 3 | |
| Factor IX, functional (%) | <1.5 | 85.4 | 88.6 | 4.2 | 29 | 82.3 | 84.8 | 3.1 | 46 |
| 1.5-1.9 | 72.57 | 73.77 | 4.9 | 30 | 78.3 | 77.0 | 3.4 | 19 | |
| 2-2.9 | 66.4 | 70.8 | 4.7 | 34 | 80.0 | 80.2 | 7.4 | 10 | |
| ≥3 | 53.5 | 55.6 | 4.1 | 12 | 74.8 | 81.9 | 13.8 | 3 | |
| Factor X, functional (%) | <1.5 | 65.4 | 71.6 | 3.3 | 30 | 91.3 | 92.1 | 1.8 | 46 |
| 1.5-1.9 | 46.7 | 47.1 | 2.9 | 32 | 76.7 | 80.0 | 3.3 | 19 | |
| 2-2.9 | 24.2 | 20.4 | 2.5 | 36 | 86.3 | 84.3 | 5.8 | 10 | |
| ≥3 | 9.0 | 10.4 | 0.9 | 14 | 61.7 | 53.1 | 9.9 | 3 | |
Abbreviations: INR, international normalized ratio; SAC, sepsis-associated coagulopathy; SEM, standard error of the mean.