Table 2.

Interventions/Procedures Performed in (A) the Prophylactic and (B) the Treatment Cohort, by Treatment Administered.

(A) Prophylactic Cohort	PCC Alone, n = 16	PCC and FFP, n = 5	FFP Alone, n = 19	All Patients, n = 40
Intervention/procedure
Minor procedure	8	3	11	22
Lumbar puncture or epidural	3	0	3	6
Central venous lines–placement and removal	0	2	0	2
Arterial access	2	1	0	3
Tracheostomy	0	0	2	2
Liver biopsy	0	0	2	2
Endoscopy with/without endoscopic retrograde cholangiopancreatography (ERCP)	0	0	3	3
Chest drain with pleural aspiration	1	0	0	1
Other (including patients undergoing multiple procedures)	2	0	1	3
Major procedure	8	2	8	18
Abdominal surgery	2	0	5	7
Cranial surgery	5	1	0	6
Major vascular surgery	0	1	2	3
Other	1	0	1	2
(B) Treatment Cohort
Intervention/procedure	PCC Alone, n = 228	PCC and FFP, n = 123	FFP Alone, n = 54	All Patients, n = 405
Cardiovascular surgery	218	113	51	382
Isolated first-time CABG	60	22	23	105
Isolated aortic valve replacement	30	9	10	49
Mitral valve replacement or repair with/without tricuspid valve replacement	26	13	2	41
Aortic valve replacement with CABG	28	12	8	48
Mitral valve replacement or repair (± tricuspid valve replacement) with CABG	22	3	2	27
Multiple valve procedure with/without CABG	11	12	1	24
Simple aortic surgery	16	13	2	31
Complex aortic surgery	4	4	0	8
Other complex surgery (including endocarditis and re-do surgery)	21	25	3	49
Gastrointestinal surgery	0	7	2	9
Neurological/nervous system surgery	2	2	0	4
Musculoskeletal surgery	1	0	0	1
Other surgical procedures	7	1	1	9

Abbreviations: CABG, coronary artery bypass graft; FFP, fresh frozen plasma; PCC, prothrombin complex concentrate