Table 3.
Parameters of APTT Waveform in Patients With Hemophilia With or Without Inhibitor, Those With VWD, and Patients With LA.
| LA | Hemophilia | Hemophilia With Inhibitor | VWD | |
|---|---|---|---|---|
| Peak of acceleration | 64.8 (44.5-79.6) | 53.9 (44.1-66.5) | 112 (69.0-120) | 46.7a (32.5-59.5) |
| Height of acceleration-1 | 159 (69.1-411) | 237 (161-354) | 25.3b (20.9-33.5) | 397a (360-510) |
| Height of acceleration-2 | 47.6 (34.0-100) | 93.7 (57.2-167) | 5.01b (3.90-5.80) | 241c (176-257) |
| Width of acceleration-1 | 26.7 (15.4-38.6) | 20.0 (15.7-28.0) | 43.2 (23.1-88.7) | 13.4 (10.4-22.1) |
| Width of acceleration-2 | 47.6 (34.0-100) | 49.4 (35.0-195) | 210 (40.0-283) | 41.8 (35.6-300) |
| Peak of velocity | 85.7 (3.80-165) | 64.9 (52.2-85.0)) | 154.3 (83.8-219) | 52.4 (36.8-72.4) |
| Height of velocity | 149 (87.1-215) | 155 (113-217) | 27.9c (24.7-50.7) | 209 (182-485) |
| Width of velocity | 66.3 (41.9-100) | 64.0 (50.1-100) | 234 (52.9-316) | 52.0 (43.4-100) |
| Peak of ½ fibrin formation | 79.0 (49.3-92.0) | 66.2 (54.4-104) | 159b (118-223) | 53.8 (37.9-73.7) |
| Height of ½ fibrin formation | 479 (254-589) | 443 (296-578) | 502 (252-870) | 302 (182-336) |
Abbreviations: APTT, activated partial thromboplastin time; LA, lupus anticoagulant; VWD, von Willebrand disease.
a P < .05 compared with LA.
b P < .01 compared with LA.
c P < .001 compared with LA.